Bovipour Pour-On for Beef and Dairy Cattle (Doramectin)

Tips For Use

Application:

Apply topically along the mid-line of the back in a narrow strip between the withers and tailhead. Use the dose rate, according to the weight of the animal in the weight/dose table (Dose Rate: 1mL per 10 kg bodyweight).
To obtain optimal benefit from the persistent action against the internal parasite, it is recommended that cattle that are set-stocked should be treated twice at eight-week intervals. By using in this way, Bovipour Pour-On will reduce the build-up of infective larvae on pasture and protect such as animals from parasitic gastroenteritis and parasitic bronchitis by reducing pasture larval challenge.

To obtain optimal benefit from the persistent action of Bovipour Pour-On against internal parasites, it is recommended that cattle that are set-stocked should be treated twice at eight-week intervals.  Used in this way Bovipour Pour-On will reduce the build-up of infective larvae on pasture and protect such animals from parasitic gastroenteritis and parasitic bronchitis by reducing pasture larval challenge.

General Instructions:

• Not to be used for any purpose, or in any manner, contrary to this label unless authorised under appropriate legislation.
• For best results, do not treat cattle when their hide or hair is wet.
• Do not apply to areas of skin that are contaminated with mud or manure.

Product Characteristics:

Bovipour Pour-On is a highly active broad-spectrum parasiticide for topical administration to cattle. It contains doramectin, a member of the macrocyclic lactone family of chemicals. Doramectin is isolated from the fermentation of selected strains derived from the soil organism Streptomyces avermitilis.

The primary mode of action of doramectin is to modulate chloride ion channel activity in the nervous system of nematodes and arthropods. Doramectin binds to receptors that increase membrane permeability to chloride ions, inhibiting the electrical activity of nerve cells in nematodes and muscle cells in arthropods, causing paralysis and death of the parasites. In mammals the neuronal receptors to which doramectin binds are localised within the central nervous system (CNS), a site reached by only negligible concentrations of doramectin.

• Broad-spectrum: A single treatment with Bovipour Pour-On effectively treats and controls a wide range of internal parasites (roundworms) and external parasites (arthropods) that impair the health and productivity of cattle.
• Persistent action: The persistent drug concentrations that result from the product’s unique pharmacokinetics enable it to protect cattle against parasite infection and reinfection for extended periods following treatment.
• Safety: Bovipour Pour-On has a wide margin of safety in all classes of cattle. Its broad spectrum of activity, favourable pharmacokinetics and exceptional
• toleration makes it an ideal product for application as an antiparasitic for cattle.
• Rainfast: the efficacy of Bovipour Pour-On is not adversely affected if applied when the hide is wet or if rain falls shortly after treatment. However, treatment of animals with wet hides or when rain threatens should be avoided as it is not good agricultural practice.

Restraints: 

Re-treatment interval: Do not re-treat animals for 56 days (8 weeks) after the last treatment

Safety Directions:

• Poisonous if swallowed.
• Will irritate the eyes and skin. 
• Avoid contact with skin and eyes.
• When using the product wear a face shield or goggles.
• If the product gets in the eyes, wash it out immediately with water. 
• Wash hands after use. 
• After each day’s use, wash face shields or goggles.

First Aid Instructions:

• If Poisoning Occurs, Contact a Doctor or Poisons Information Centre. Phone Australia 131126.
• If skin contact occurs, remove contaminated clothing and wash skin thoroughly.
• Additional information is listed in the Safety Data Sheet (SDS).

Environmental Protection:

• Doramectin is extremely toxic to aquatic species. Do not contaminate dams, rivers, streams or other waterways with the chemical or used container.
• When used according to label instructions, Bovipour Pour-On is not likely to have an unintended effect that is harmful to the environment or have an overall adverse impact on dung beetle populations. Increased mortality and impaired development of larvae may be expected, but for a limited period after treatment.

Storage: 

• Store below 30^oC (room temperature). 
• Protect from direct sunlight.