Name: Zolvix Plus for Sheep and Cattle
Brand: Elanco
SKU: ZOLVIX-PLUS
Availability: InStock

Zolvix Plus for Sheep and Cattle also treats and controls gastrointestinal roundworms sensitive to monepantel and/or abamectin in beef cattle and non-lactating dairy cattle.

Active Ingredients: Abamectin @ 2g/L and Monepantel @ 25g/L

Click For Technical Info & Tips For Use

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Description

Zolvix Plus for Sheep and Cattle

Active Ingredients: Abamectin @ 2g/L and Monepantel @ 25g/L

Zolvix Plus for Sheep and Cattle is a ready-to-use oral drench for the treatment and control of gastrointestinal roundworms sensitive to monepantel and/or abamectin in sheep, including strains resistant to macrocyclic lactones, benzimidazoles, levamisole or closantel drenches (Haemonchus contortus only), and their combinations. Zolvix Plus for Sheep and Cattle also treats and controls gastrointestinal roundworms sensitive to monepantel and/or abamectin in beef cattle and non-lactating dairy cattle.

Zolvix Plus for Sheep and Cattle contains Monepantel, a member of the class of anthelmintics called the Amino-Acetonitrile Derivatives (AADs) while Abamectin is a member of the Macrocyclic Lactone (ML) class of anthelmintics.

Why choose Zolvix Plus for Sheep and Cattle;

Sheep:
- A unique mode of action with a broad spectrum of activity.
- Greater than 99.9% efficacy against a broad spectrum of internal parasites.
- Controls single, double and triple drench resistant worm strains which delays the development of drench resistance.
- 21 day ESI and 14 day meat WHP for sheep.
- A short-acting, broad-spectrum combination drench.
- Incorporating Monepantel into drenching programs can help to prolong the life of all effective drenches against resistance.
- Can be used as a knockout, exit or quarantine drench in drench programs.
- Ideal for use in strategic drenching programs as a summer (WA: autumn), pre-lambing, weaning or quarantine drench.
Cattle:
- Provides fully-effective, broad spectrum control of key worm species.
- Ideal rotation drench for white, clear and mectin drenches.
- An essential quarantine drench.
- Ideal for young cattle, particularly at weaning.
- Can be administered to beef and dairy calves over 100kg and 16 weeks of age and older.
- Ease of administration with a 30mL Oral Drencher.

What is the parasite efficacy spectrum of Zolvix Plus for Sheep and Cattle;

Sheep

Barber’s pole worm: Haemonchus contortus**
Small brown stomach worm: Ostertagia (Teladorsagia) circumcincta*, Ostertagia
(Teladorsagia) trifurcata*, Ostertagia (Teladorsagia) davtiani*, Ostertagia (Teladorsagia) spp.**
Black scour worm: Trichostrongylus colubriformis*, Trichostrongylus vitrinus*, Trichostrongylus rugatus*
Stomach hair worm: Trichostrongylus axei*
Thin necked intestinal worm: Nematodirus filicollis*, Nematodirus spathiger*;
Small intestinal worm: Cooperia curticei*, Cooperia oncophora*
Large mouthed bowel worm: Chabertia ovina*
Large bowel worm: Oesophagostomum venulosum*
- * Includes adult and immature L4 stage
- ** Includes adult, immature L4 stage and inhibited L4 stage

Cattle:

Barbers pole worm: Haemonchus placei*
Small brown stomach worm: Ostertagia ostertagi*
Stomach hair worm: Trichostrongylus axei*
Small intestinal worm: Cooperia oncophora*, Cooperia pectinata*, Cooperia punctata*, Cooperia mcmasteri*
Thin necked intestinal worm: Nematodirus helvetianus*
Hookworm: Bunostomum phlebotomum**
Nodule worm: Oesophagostomum radiatum**
- * Includes adult and immature L4 stage
- ** Includes adult stage only

What is the mode of action of Zolvix Plus for Sheep and Cattle

Amino-Acetonitrile Derivatives (AADs) have a completely unique mode of action compared to all other anthelmintics available on the market. Monepantel causes a paralysis of the worms by binding to a specific receptor that is only found in nematode parasites (roundworms). It is believed that the high margin of safety in sheep and cattle, and environmental safety of Zolvix Plus for Sheep and Cattle is attributable to the fact that the specific receptor for the AADs has not been found in any animal species other than nematodes. Abamectin causes paralysis and death of target organisms via the activation of a glutamate-gated chloride channel present in invertebrate nerve and muscle cells, and/or through the effect on gamma-aminobutyric acid (GABA) receptors.

Zolvix Plus for Sheep and Cattle Pack Sizes: 1L, 5L and 10L

Registrant: Elanco Australasia Pty Ltd (APVMA #: 69763

Elanco Websites for Zolvix Plus for Sheep and Cattle

Sheep – Here

Cattle – Here

Cattle Drench Product Range

Sheep Drench Product Range

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Features & Benefits

Sheep:
- A unique mode of action with a broad spectrum of activity.
- Greater than 99.9% efficacy against a broad spectrum of internal parasites.
- Controls single, double and triple drench resistant worm strains which delays the development of drench resistance.
- 21 day ESI and 14 day meat WHP for sheep.
- A short-acting, broad-spectrum combination drench.
- Incorporating Monepantel into drenching programs can help to prolong the life of all effective drenches against resistance.
- Can be used as a knockout, exit or quarantine drench in drench programs.
- Ideal for use in strategic drenching programs as a summer (WA: autumn), pre-lambing, weaning or quarantine drench.
Cattle:
- Provides fully-effective, broad spectrum control of key worm species.
- Ideal rotation drench for white, clear and mectin drenches.
- An essential quarantine drench.
- Ideal for young cattle, particularly at weaning.
- Can be administered to beef and dairy calves over 100kg and 16 weeks of age and older.
- Ease of administration with a 30mL Oral Drencher.

Directions Of Use

Click here for Zolvix Plus for Sheep and Cattle directions for use.

Dosage: Sheep: The dose rate for sheep and lambs is 0.5 mL/5kg (1 mL/10 kg)

Bodyweight (Kg)	Dose (mL)
10-15	1.5
16-20	2.0
21-25	2.5
26-30	3.0
31-35	3.5
36-40	4.0
41-50	5.0
51-60	6.0
61-70	7.0
71-80	8.0

Sheep in excess of 80 kg body weight should be dosed at 1 mL/10 kg.

Dosage Cattle: The dose rate for cattle is 5mL/50 kg (10mL/100kg)

Bodyweight (Kg)	Dose (mL)
100	10
101-120	12
121-150	15
151-200	20
201-250	25
251-300	30
301-350	35
351-400	40
401-450	45
451-500	50
501-550	55
551-600	60
601-650	65

Cattle in excess of 650 kg body weight should be dosed at 5 mL/50 kg.

Administration:

Use remaining product within 12 months of opening the container.
Zolvix Plus for Sheep and Cattle is a ready to use oral solution.
Check dose rates and drench gun before treatment commences.
Drench animals orally using an Elanco recommended drench gun.
Maintain applicator gun carefully to ensure accurate dosage.
After use, clean gun by flushing with warm, soapy water. Rinse with cold water.
A representative sample of animals should be weighed before treatment.
Calculate the dose rate based on the animals to the heaviest live weight in each group.
Do not underdose.
Where there is a large variation in weight within the group, dose should be based on the label directions for each weight range.
Drafting into two or more lines may be appropriate, to avoid excessive overdosing.
A correct drenching technique is recommended; carefully place the drench gun nozzle in the side of the mouth and over the back of the tongue before delivering the dose.

Rates are a general guide only. Before opening, carefully read Zolvix Plus for Sheep and Cattle directions for use, precautionary and protection statements, storage and disposal, safety directions and first aid instructions. The product is designed for the particular purpose indicated on the label. Failure to use the product strictly as directed may be illegal and dangerous and render the product ineffective.

Questions and answers from customers

Does Zolvix Plus Sheep Drench have a withholding period for milk?

Q Does Zolvix Plus Sheep Drench have a withholding period for milk?
Asked by Alison on February 23, 2025 8:24 pm

Answered by the admin
Zolvix Plus Sheep Drench does have a withhold for milk. For sheep, this is; 'Do not use in ewes that are producing or may in the future produce milk that may be used or processed for human consumption', and for cattle, this is; 'Do not use in lactating cows or within 49 days of calving, where milk may be used or processed for human consumption'.

Can Zolvix Plus Sheep Drench be used on goats? If not, why?

Q Can Zolvix Plus Sheep Drench be used on goats? If not, why?
Asked by Sophie Kate on October 21, 2022 2:21 pm

Answered by the admin
Zolvix Plus Sheep Drench is only registered for use on Sheep. Specialist Sales is limited to providing advice based on the registered APVMA uses per the product's label. However, a veterinarian may be able to provide 'off-label' recommendations for use on animals other than Sheep.

The products recommended for use on goats include Alben Broad Spectrum Anthelmintic For Sheep, Lambs & Goats, Panacur 25 Oral Anthelmintic For Sheep, Cattle and goats, and Livamol with Bioworma are drenches registered for use on goats.

What length of time will Zolvix Plus Broad Spectrum Oral Sheep Drench be active in sheep?

Q What length of time will Zolvix Plus Broad Spectrum Oral Sheep Drench be active in sheep?
Asked by Petes Stewart on May 15, 2022 9:16 am
Answered by the admin
Zolvix Plus Broad Spectrum Oral Sheep Drench is a short-acting drench passed through the animal within a matter of days. It does not provide long-acting residual control of internal parasites. Highly effective, short-acting drenches help avoid parasite resistance to the active ingredients being used.

Elanco recommend you always administer Zolvix Plus in compliance with best practice;

Test and monitor drench efficacy regularly

Only use ‘fully effective’ drenches

Use combination drenches wherever possible

Only use long-acting products during high worm-risk conditions and in combination with a primer/exit drench

Quarantine drench all introduced/returning sheep with four active ingredients (including monepantel or derquantel)

Incorporate grazing management to create ‘low risk’ pastures

Is the ESI for Zolvix Plus Broad Spectrum Oral Sheep Drench still 84 days in Australia? I have been told that it has been changed to 21 days.

Q Is the ESI for Zolvix Plus Broad Spectrum Oral Sheep Drench still 84 days in Australia? I have be...... Read more
Asked by Barry Chapman on February 25, 2022 6:19 am
Answered by the admin
The updated ESI for Zolvix Plus Broad Spectrum Oral Sheep Drench according to the APVMA is;

Export Slaughter Interval (ESI):

Sheep: Do not use less than 21 days before slaughter for export.

Before using this product, confirm the current ESI from Elanco Australasia on 1800 226 324 or the APVMA website (www.apvma.gov.au/residues).

Is this safe in pregnant animals?

Q Is this safe in pregnant animals?
Asked by Jodie Burr on January 16, 2022 9:39 pm

Answered by the admin
The Zolvix Plus Broad Spectrum Oral Sheep Drench has a high margin of safety in sheep and cattle. However, the products label does not reference safety when used on pregnant animals. We recommend consulting your local veterinary practitioner or animal health advisor before use. Alternatively, you can check with Elanco on 1800 226 324.

Disclaimer: This information and product advice is not intended to be advice or recommendations for any specific use or circumstance. You should seek specialist advice before using any product. Always follow the manufacturer’s guidelines. Specialist Sales liability is limited.

Host & Pest

Host	Pest
Host & Pest
Beef Cattle - Adult & Dairy Cattle, Not Lactating & Not Pregnant	Barber's Pole Worm - Haemonchus Placei, Cooperia Mcmasteri, Cooperia Pectinata, Cooperia Punctata, Hookworm - Bunostomum Phlebotomum, Nematodirus Helvetianus, Nodule Worm - Oesophagostomum Radiatum, Small Brown Stomach Worm - O. Ostertagi, Small Intestinal Worm - C. Oncophora, Stomach Hair Worm - T. Axei
Sheep - Over 10kg (Body Weight)	Black Scour Worm - T Colubriformis, Cooperia Oncophora, Large Bowel Worm - O. Venulosum , Ostertagia Davtiani, Small Brown Stomach Worm-Ostertagia Spp., Small Intestinal Worm - C. Curticei, Stomach Hair Worm - T. Axei, Thin Necked Intestinal Worm, Thin Necked Intestinal Worm N. Spathiger, Trichostrongylus Rugatus, Trichostrongylus Vitrinus

Tips For Use

General:

Use remaining product within 12 months of opening the container.

Restraints:

Do not use in sheep less than 10 kg body weight.
Do not use in cattle less than 100 kg body weight.
Do not use in ewes which are producing or may in the future produce milk that may be used or processed for human consumption.
Do not use in lactating cows or within 49 days of calving where milk may be used or processed for human consumption.

Re-treatment interval:

Sheep: Do not re-treat animals for 42 days after the last treatment.
Cattle: Do not re-treat animals for 21 days after the last treatment.
After three consecutive treatments, 61 days must elapse before treating again.

Contraindications:

This product is contraindicated for use in lambs under 6 weeks of age or less than 10 kg body weight.
This product is contraindicated for use in calves under 16 weeks of age or less than 100 kg body weight.
This product should not be used in dogs, horses or any other pets.
This product is not recommended for use in goats as safety and efficacy have not been evaluated.

Precautions:

Safety in breeding cattle and pregnant or lactating cows has not been established.

Environmental Protection:

Do not contaminate dams, rivers, streams or other waterways with the chemical or used container.

Storage:

Store below 30 °C (room temperature).
Store in the original tightly closed container.
Protect from light.

Safety Directions:

Repeated exposure may cause allergic disorders.
Sensitive workers should use protective clothing.
When opening the container and using the product, wear elbow length chemical-resistant gloves.
If product is on the skin, immediately wash the area with soap and water.
Wash hands after use.
After each day of use, wash gloves.

First Aid:

If skin contact occurs, remove contaminated clothing and wash skin thoroughly.
If poisoning occurs, contact a doctor or the Poisons Information Centre. Phone Australia 131 126.
For further information, refer to the Safety Data Sheet (SDS).

This information and product advice is not intended as advice or recommendations for any specific use or circumstance. You should seek specialist advice before using any product. Always follow the manufacturer’s guidelines. Specialist Sales liability is limited.

How to drench orally.

Withholding Period

Withholding Period Details: (WHP)

Meat (Sheep): Do not use less than 14 days before slaughter for human consumption.
Meat (Cattle): Do not use less than 12 days before slaughter for human consumption.

Export Slaughter Interval (ESI):

Sheep: Do not use less than 21 days before slaughter for export.
Cattle: Do not use less than 61 days before slaughter for export.

Before using this product, confirm the current ESI from Elanco Australasia on 1800 995 709 or the APVMA website (www.apvma.gov.au/residues).

SDS & Technical

Zolvix Plus for Sheep and Cattle Label (APVMA)	Download Pdf
Zolvix Plus for Sheep and Cattle SDS	Download Pdf

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