Description
How does Exzolt Pour-on for Cattle work?
Fluralaner belongs to the isoxazoline parasiticide class, and features a chemistry that is entirely new to the Australian cattle market. It has a dual mode of action — systemic absorption into the bloodstream via grooming and direct skin contact, combined with contact activity on the animal’s surface. When cattle ticks, bush ticks, or buffalo flies feed on or contact a treated animal, they are exposed to a lethal dose of fluralaner.
This dual pathway, combining systemic and contact action, ensures greater parasite exposure than products that rely solely on systemic activity, contributing to the rapid knockdown effects Exzolt is able to deliver within one to five days of application.
Which parasites does Exzolt Pour-on for Cattle control?Â
Exzolt Pour-on for Cattle is registered to control a number of external parasites commonly found in cattle in Australia, including:Â
- Bush tick (Haemaphysalis longicornis) — control for 21 days
- Buffalo fly (Haematobia irritans exigua), including synthetic pyrethroid-resistant strains — control for 21 days
- Cattle tick (Rhipicephalus [Boophilus] microplus), including strains resistant to dieldrin, organophosphates (OPs), synthetic pyrethroids (SPs), amidines (amitraz), macrocyclic lactones (MLs), and fluazuron — control for 56 days
The 56-day cattle tick control period is the longest offered by any pour-on parasiticide currently registered in Australia. This extended protection period means fewer treatments per year, less handling stress on cattle, and reduced labour and product costs during peak tick season.
How Exzolt can help to effectively manage resistance in Australia
Cattle tick resistance to conventional parasiticides (specifically, acaricides like SPs and OPs), is one of the most serious challenges facing Australian beef producers in Queensland, northern New South Wales, and the Northern Territory.
On many properties, ticks have developed resistance to multiple chemical classes. Properties with the Ultimo strain (resistant to SPs, OPs, and amitraz) have historically been limited to macrocyclic lactone pour-ons as their only remaining treatment option. These products are typically slower-acting and more labour-intensive than plunge dips.
Exzolt Pour-on for Cattle changes this equation. As the first isoxazoline for cattle in Australia, fluralaner offers a new mode of action with no known resistance in Australian tick or buffalo fly populations. It is effective against strains that have defeated every other available chemical class, giving producers with multi-resistant properties a viable, long-lasting treatment option where few existed before.
Where Exzolt fits in a rotation program
Exzolt should be used strategically as part of an integrated tick management program, not as a standalone treatment used every cycle. Rotating with other effective chemical groups will help to preserve fluralaner’s efficacy and longevity. The goal is to keep this formulation and unique chemistry working for as long as possible to ensure long-term success.
Frequently asked questionsÂ
How does Exzolt compare to Cydectin Pour-On for addressing cattle tick?
Where Exzolt Pour-on for Cattle provides 56 days of protection against cattle tick, Cydectin Pour-On (formulated with moxidectin) only provides 21. Both are pour-on treatments, but Exzolt offers nearly three times the protection period per every treatment. More importantly, Exzolt controls tick strains that are resistant to macrocyclic lactones, which Cydectin does not.
Is Exzolt rainfast?
Yes. It is not adversely affected by heavy rainfall after treatment, once applied, its efficacy is maintained regardless of weather conditions.
Can I use Exzolt on pregnant or breeding cows?
Yes, Exzolt Pour-on for Cattle is safe for use in breeding and pregnant cows. However, it cannot be used on animals weighing less than 70kg.
Should Exzolt be used repeatedly?
No, it should always be strategically rotated with other treatments. Using any single active ingredient will repeatedly accelerate resistance development on your property. For best results, incorporate Exzolt into a broader tick management rotation that includes other effective chemical groups available to you.
SarahG (verified owner)
It took a few days to work but the results are impressive. All the stock are so much more comfortable and hopefully we will reduce the tick population in the paddocks.
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