Description
How Surefire Amine 625 Herbicide works
Surefire Amine 625 is formulated with 2,4-D, which works by mimicking the natural plant growth hormone auxin. After application to susceptible broadleaf weeds, the chemical is translocated throughout the plant’s leaves and stems and begins to disrupt its hormonal balance, triggering uncontrolled cell division and elongation. Symptoms like twisting, curling, and wilting will occur within around 1 to 3 days, with full plant death following in 7 to 14 days.
Importantly, grasses are naturally tolerant to auxin-based herbicides, which is why Surefire Amine 625 is able to control broadleaf weeds without damaging cereal crops, pasture grasses, or common turf species.
Common weeds controlled by Surefire Amine 625 Herbicide
Surefire Amine 625 controls an incredibly wide range of broadleaf weed species, including the following:
| Afghan Melons | Charlock | Hoary Cress | Paterson’s Curse | Spear Thistle |
| Amaranthus Spp. | Chinese Mint | Hogweed | Perennial Pigweed | Speedwell – Ivy Leaf |
| Amsinckia | Clockweed | Horehound | Pimelea Sp. | Spiny Emex |
| Annaul Pigweed | Clover | Indian Hedge Mustard | Pink Convolvulus | Spinyhead Sida |
| Annual Thistles | Cobblers Pegs | Ipomea Vines | Pink Flowered Burr | Star Burr |
| Apple Of Peru | Common Ice Plant | Jute | Pinkburr | Star Of Bethlehem |
| Artichoke Thistle | Common Sida | Khaki Weed | Potato Weed | Star Thistle |
| Bathurst Burr | Common Sowthistle | Knobweed | Prickly Saltwort | Stinkwort |
| Bellvine | Convolvulus | Kyalinga Weed (Whisker Grass) | Purple Top (Verbena Bonariensis) | Storksbill |
| Billygoat Weed | Cupid’s Flower | Lantana | Ragwort | Thornapple |
| Bindweed | Dock | Leucas | Rapeseed | Three-Cornered Jack |
| Bindy Eye | Doublegee | Lincoln Weed | Rapistrum | Tridax (Tridax Daisy) |
| Blackberry Nightshade | Doveweed | London Rocket | Roly Poly | Variegated Thistle |
| Blackeyed Susan | Erodium | Lupin | Rough Poppy | Vetches/Tares |
| Blue Heliotrope | Fat Hen | Matricans | Rubber Vine | Vines |
| Blue Snakeweed | Flannel Weed | Melilotus | Safflower | Wards Weed |
| Blue Top | Flatweed | Milky Cotton Bushes | Saffron Thistle | Water Hyacinth |
| Boneseed | Fleabane | Mintweed | Scarlet Pimpernel | Water Primrose |
| Boxthorn | Fumitory – Red & White | Morning Glory | Sesbania Pea | Weir Vine (Ipomea) |
| Burr Medic | Galvanised Burr | Mother Of Millions | Shepherd’s Purse | White Eye (Mexican Clover) |
| California Burr | Geranium | Mustard | Shore Thistle | Wild Cabbage |
| Californian Thistle | Groundsel | Needle Burr | Siratro (Purple Bean) | Wild Poppy |
| Caltrop | Hawthorn | New Zealand Spinach | Skeleton Weed | Wild Radish |
| Cape Tulip | Heliotrope | Noogoora Burr | Slender Thistle | Wild Tobacco Tree |
| Capeweed | Hemlock | Paddy Melons | Soldier Thistle | Wild Turnip |
| Castor Oil Plant | Hexham Scent | Parthenium Weed | Sorrel | Wireweed |
Always refer to the Product Label for a comprehensive list of weed species controlled, including any conditions.
Why is Surefire Amine 625 so beneficial for controlling broadleaf weeds?
This 2,4-D weedkiller is particularly effective for a handful of reasons. Its 625g/L concentration is highly potent compared to other, lower-strength formulations on the market, meaning you need less product per hectare and can get more coverage from each container. It also leaves no persistent soil residue, so you can confidently rotate it into subsequent crops or pastures without plant-back concerns beyond the standard label requirements.
For cereal growers dealing with herbicide-resistant wild radish populations, Surefire 2,4-D herbicide offers an effective Group 4 rotation option as part of an integrated weed management strategy. By offering a different mode of action to the Group 2 (ALS inhibiting) herbicides that many wild radish populations have formed resistance to, you’re increasing your chances of control.
Using Surefire Amine 625 Herbicide as a broadleaf weed killer
When to apply
Surefire Amine 625 Herbicide offers a wide application window in cereals, starting from the 5-leaf or 2-tiller stage, through tillering and up to jointing (roughly 8 to 14 weeks after sowing).
For pre-sowing knockdown, this product controls emerged broadleaf weeds in fallow before direct drilling or sowing cereals, grain legumes, and canola.
In pastures, it is particularly useful when paired with the spray-grazing technique, wherein increased stocking rates on sprayed pastures forces livestock to graze treated weeds, maximising legume seed set while reducing weed seed set ahead of broadacre cropping.
Application rates and methods for Surefire Amine 625
Application rates for this Group 4 herbicide for broadleaf control will vary by situation. Lawns and playing fields typically require between 15 and 30mL per 10L of water (or 1.6 to 3.2L/ha), whereas pasture and cropping rates range from 280mL to 3.2L/ha, depending on the target weed, state requirements, and situation. Please refer to the Product Label for state-specific rates, as these vary considerably dependent on local regulations.
Surefire Amine 625 Herbicide mixes readily with water, and is compatible with glyphosate for tank-mixing in fallow applications. It can be applied via boom sprayer (30 to 120L/ha water volume) or aerial equipment (10 to 90L/ha water volume).
For specific advice, including rates, withholding periods, and state-based restrictions, refer to the Product Label.
Safety considerations
Surefire Amine 625 is a phenoxy herbicide and can cause severe damage to susceptible crops including cotton, grapes, tomatoes, oilseed crops, and ornamentals. Avoid spray drift onto sensitive vegetation, and do not use spray equipment for other purposes unless thoroughly cleaned beforehand. Always observe a 7-day grazing withholding period for pastures and cereal crops.
Frequently asked questions
Can Surefire Amine 625 be mixed with glyphosate?
Yes, Surefire Amine 625 Herbicide can be mixed with glyphosate — in fact, tank-mixing the active ingredient, 2,4-D, with glyphosate is a common and effective practice for pre-sowing fallow knockdown. This is because the two herbicides target different plant processes — glyphosate controls grasses and broadleaf weeds non-selectively, whereas 2,4-D provides stronger broadleaf knockdown. Together, they deliver better broader spectrum control than each active individually.
Is Surefire Amine 625 the same as Amicide or Conquest Amine 625?
All three products — Surefire Amine 625 Herbicide, Amicide 2,4-D 625 Amine Selective Herbicide, and Conquest Amine 625 Herbicide, contain the same active ingredient and are registered for the same uses. Surefire Amine 625 is essentially a generic option that offers the same broadleaf weed control at a more manageable price point.
When is the best time to spray 2,4-D on pastures?
2,4-D-based products like Surefire should be applied to young and actively growing broadleaf weeds for best results. In most Australian regions, autumn and spring are optimal timing windows, as weeds are small and actively growing. Avoid spraying under hot, windy, or drought-stressed conditions, as efficacy will be reduced and drift risk can increase.




Brian (verified owner)
Good all round spray
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Diane Crawford (verified owner)
I have purchased items on two occasions. Advice on the products has been very helpful, with genuine interest and assistance with suggestions for the best product to use for the specific situations. Service was very speedy, next day delivery, and items were well packaged. I will certainly recommend your service to others.
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jim martin (verified owner)
Good product,arrived quickly,well packaged and really good service over the phone.As good as it gets.Thank you
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Darryl Holt (verified owner)
It works well.
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Carolyn Dean (verified owner)
This seems to be the only thing that will eradicate this pest of a plant.
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